Antioxidant capacity and toxicologic potential of Ibervillea sonorae plant
Capacidad antioxidante y potencial toxicológico de la planta Ibervillea sonorae
DOI:
https://doi.org/10.54167/tecnociencia.v16i2.903Palabras clave:
Ibervillea sonorae, infusiones, capacidad antioxidante, citotoxicidad, genotoxicidadResumen
El objetivo principal de este estudio fue evaluar la capacidad antioxidante y posible potencial toxicológico de las infusiones preparadas a partir de Ibervillea sonorae. Para esto, se prepararon infusiones a partir de la raíz de I. sonorae, usando la piel o la pulpa. La capacidad antioxidante de las infusiones fue evaluada mediante los ensayos de ABTS y DPPH. Mientras que, el modelo de Artemia salina, el ensayo MTT usando células Vero y MCF-7, y la prueba de Ames fueron usados para evaluar el posible potencial toxicológico. Los resultados mostraron que las cáscaras de I. sonoraeeran más letales (60 - 80%) que las de pulpa (<50%). De manera interesante, la pulpa de I. sonorae mostró una mayor toxicidad sobre células Vero (IC50 = 222 µg/mL) que las infusiones realizadas usando las pieles (IC50 = 379 µg/mL). Las infusiones de I. sonorae, ya sea en forma de cáscara o pulpa, mostraron una alta mutagenicidad a 1000 y 500 µg/mL. La ingesta de infusiones preparadas a partir de la planta de I. sonorae podría ocasionar graves daños a la salud.
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