Anovulación, un problema de salud pública

Anovulation, a problem of public health

Authors

  • Adolfo Aguilar-Cobos UACH. Facultad de Medicina
  • Javier Aguilar-Natividad Residente 3er año Ginecología y Obstetricia Christus Muguerza del Parque

DOI:

https://doi.org/10.54167/tecnociencia.v2i3.80

Keywords:

Anovulation-Hormones-Polypharmacy Multiple Pregnancy-OHSS

Abstract

Infertility is a public health problem, the most common factor is anovulation. Here we describe a brief historical account of different techniques and hormones used. It is demonstrated its use with little knowledge, not an evidence-based medicine, its frequent and serious complications. In its application we alter the physiology of the axis hypothalamus-pituitary-ovary, with its consequences such as multiple pregnancies, prematurity, Ovaric Hyperstimulation Syndrom (OHSS), as well as very high costs.
What will be an ideal drug to induce ovulation?

DOI: https://doi.org/10.54167/tecnociencia.v2i3.80

Downloads

Download data is not yet available.

References

Barri, P. N., F. Martinez, B. Coroleu, A. Veiga & G. Calderón. 1988. Experiencia clínica de la utilización de antagonistas de la GnRH en un programa de fertilización in Vitro (FIV). Drugs of Today 24:51-60.

Braat, D. D., D. Ayalon, S.M. Blunt, D. Bogchelman, H.J. Coelingh, D.J. Handelsman, M.J. Heiman, R. E. Lappöhn, R.H. Lorijin & R. Rolland. 1989. Pregnancy Outcome in luteinizing Hormone-releasing hormone induced cycles: a multicentre study. Gynecological Endocrinology 3(1):35-44. https://doi.org/10.3109/09513598909152450

Lunenfeld, B. 1995. Profesor emérito de Endocrinologia en el Departamento de Ciencias de la Vida de la Universidad Barllan en Ramat Gan, Israel. Este artículo se basa en la ponencia impartida por el profesor Lunenfeld en el congreso de la ESHRE celebrado en 1995 en Hamburgo, Alemania, después de haber sido nombrado miembro honorario.

Gemzell, C. A. 1966. Leading Men of Science. Triangle 7:331-332.

Dutta, A. S. 1989. Chemistry of GnRH analogues. En GnRH Analogues in Cancer and Human reproduction. Basic Aspects (p. 33). Kluwer Academic Publishers. ISBN 0792389328, 9780792389323.

Green, J. D. & G. W. Harris. 1949. Observation of the hipophysio-portal vessels in the living rat. The Journal of Physiology 108(3):359-361.

Hazum, E., M. Fridkin, T. Baram & Y. Koch. 1981. Degradation of gonadotropin releasing hormone by anterior pituitary enzymes. FEBS Letters 127(2):273-276. https://doi.org/10.1016/0014-5793(81)80222-0

Homburg, R. & V. Insler. 2002. Ovulation induction in perspective. Human Reproduction Update 8(5): 449-462. https://doi.org/10.1093/humupd/8.5.449

Karten, M. J. & J. E. River. 1986. Gonadotropin-releasing hormone analog design. Structure-funtion studies toward the development of agonists and antagonists: rational and perspective. Endocrinology Review 7(1):44-66. https://doi.org/10.1210/edrv-7-1-44

Letterie, G.S, C.C. Coddington, R. L. Collins & G.R. Merriam. 1996. Ovulation induction using s.c. pulsatile gonadotrophin- releasing hormone. Effectiveness of different pulse frequencies. Human Reproduction 11(1): 19-22. https://doi.org/10.1093/oxfordjournals.humrep.a019015

Martin, K. A., J. E. Hall, J. M. Adams & W.F. Crowley Jr. 1993. Comparison of exogenous gonadotropins and pulsatile gonadotropin-releasing hormone for induction of ovulation in hypogonadotropic amenorrea. The Journal of Clinical Endocrinology & Metabolism 77(1): 125-129. https://doi.org/10.1210/jcem.77.1.8325934

Medvei, V.C. 1993. The history of clinical endocrinology: A comprehensive account of endocrinology from earliest times to the present day. Parthenon Publishing Group. ISBN 1850704279.

Seminara, S.B., M. Beranova, L. M. Oliveira, K. A. Martin, W.F. Crowley Jr & J.E. Hall. 2000. Successful use of pulsatile gonadotropin-releasing hormone (GnRH) for ovulation induction and pregnancy in a patient with GnRH receptor mutations. The Journal of Clinical Endocrinololgy & Metabolism 85(2): 556-562. https://doi.org/10.1210/jcem.85.2.6357

Sirpa, V. 1998. Estudio sobre la viabilidad clínica de la transferencia de un sólo embrión. IVF News 9(4).

Starling, E. 1923. The Wisdom of the Body. The Harveian Oration. British Medical Journal 2(3277): 685-690. https://doi.org/10.1136%2Fbmj.2.3277.685

Ulla, B. W. 1998. Estudio nacional sueco registra los efectos de los embarazos múltiples. IVF News 9(4).

Wade, N. 1978. Rough journey to a Nobel Prize. New Scient 219-221.

Published

2018-11-14

How to Cite

Anovulación, un problema de salud pública: Anovulation, a problem of public health. (2018). TECNOCIENCIA Chihuahua, 2(3), 166-171. https://doi.org/10.54167/tecnociencia.v2i3.80